The SMPD1 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to acid sphingomyelinase, aSMase, and SMPD1. This antibody recognizes Human, Mouse, and Rat antigen. The SMPD1 Polyclonal Antibody has been validated for the following applications: Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified